The quality of the study was assessed using jadad scale assessment tool for clinical trial studies. We systematically searched the pubmed, europe pmc and clinicaltrials.gov database using specific keywords related to our aims until 10th may 2021.

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Two groups, the study group and the control group, took part in the study.

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Ivermectin and covid clinical trials. Actual primary completion date : Actual study completion date : This drug was well tolerated, with a good tolerability profile and few adverse events with oral administration.

Most compared ivermectin with placebo or no ivermectin; Ivermectin is a widely used broad spectrum antiparasitic. Larger trials will be needed to confirm these preliminary findings.

The ascot team is very aware of the challenges of developing and conducting randomised trials in pandemic conditions, but we’re committed to it because clinical trials are the best way to offer patients new therapies and generate the evidence needed to use them ethically. Actual study start date : 3 trials included an active comparator (table (table1).

There were no severe adverse drug events recorded in the study. There are mixed results in clinical trials. All published randomized clinical trial studies on covid‐19 and ivermectin were retrieved.

Much of the randomised clinical trial evidence consists of trials of low methodological quality, for the most part with small sample sizes and disparate interventions and controls, limiting the confidence in any conclusions with respect to ivermectin. Further studies with larger sample sizes, different drug dosages, dosing intervals and durat.

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